Joint Recovery, Prehab, and the Promise Around Peptides

Joint Recovery, Prehab, and the Promise Around Peptides

Injury recovery is where hope and hype often meet. Surgery, platelet-rich plasma, peptides, robotics, and prehab all promise a better return. The clearest message is that tissue recovery still depends on diagnosis, loading, inflammation (covered in detail here) control, and skilled clinical judgment.

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Joint Recovery, Prehab, and the Promise Around Peptides: Full Transcript

Transcript from Dr. Jason Snibbe: Peptides for ACL Recovery, BPC-157 & TB-500, Robotic Surgery, & Prehab | TUH # 278.

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Our goal is to walk within an hour of the surgery. There's enormous amount of data showing that if you get up and walk on your joint replacement immediately, your confidence goes through the roof of trusting the joint. I love thought leaders like yourself that are really patient-centric and thinking about what is the best possible outcome for this patient to get back to full life. It's like you're an artist. You want that canvas to be good quality canvas. So, if the canvas or the patient is not quality, they don't have good tissue or good metabolism and good health, no matter how great of a painting you draw, no matter how great of a surgery you do, you're going to have a bad outcome. The focus on prehabilitation, post-habilitation, minimally invasive surgery, and the use of all of the biohacking modalities tells me that you're really focused on the whole patient journey. My big passion is controlling the episode of care for these patients. Where do you see the the future of orthopedic surgery going? I think the future of orthopedic surgery will be Hey guys, welcome back to the Ultimate Human podcast. I'm your host, human biologist Gary Brecka, where we go down the road of everything anti-aging, biohacking, longevity, and everything in between. And today is going to be one of those really fascinating, what I would call the in-between podcasts, because we're going to look at a classically trained surgeon who is doing some phenomenal things, not just with joint replacements, but with surgical interventions, minimally invasive, sparing as much muscle as possible, and getting patients back to to activity faster than traditional methods. And what I love about this surgeon is that he is also a biohacker. He's He's as curious as I am about ways that we can improve outcomes using things like nutrition and biohacking modalities to

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nutrition and biohacking modalities to improve these surgical outcomes. So, welcome to the podcast, Dr. Jason Snibbe. Thank you for having me, Gary. Board-certified orthopedic surgeon and slash biohacker. That's right. I love it. In fact, I I wrote something down here that I thought was really cool way to start the podcast. Prehab is the missing biohack. Yes. Certainly heard of rehab, but I've never heard of prehab. [laughter] Absolutely. And um you know, before the podcast started, like a lot of my guests, we sort of ran a mini podcast in our hyperbaric chamber. Yeah, it was so nice. But I I find it really fascinating that you take this whole patient approach um to something like a surgical intervention um on a joint. And I wonder if you might just talk about that for a minute. Um what was your journey from classically trained surgeon to now being one of the pioneers and arguably one of the leading authorities um in in the world on these minimally invasive robotic surgeries and and your attitude towards this prehabilitation. I think, you know, my approach to surgery and has always been how can we make it better? What are the little things that we can do to make it better? And I when I started my career, I realized that if I'm super gentle on the tissue, I'm easy on the muscles, I don't put, you know, a traditionally these heavy retractors that would tear through muscle and tear through tissues. It's kind of brutal. Mhm. And I realized open heart surgery, like And on the rib spreader, you know. Yeah, just it's just so brutal. And I realized if I just am gentle, then when I would go see the patient the next day in the hospital, I'd be like, "Wow, this guy's getting up out of bed. He's able to engage his muscles. He's able to move so easily and move so quickly without having all this trauma to the joint." So, everything that we traditionally do, so for example, like in a knee replacement, traditionally people put a tourniquet on your leg. A tourniquet for, you know, the case would take an hour and a half, 2 hours. It would crush

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hour and a half, 2 hours. It would crush your quad muscle. Right. For 2 hours. And so, then they would say, "Okay, get up and move." You're like, "I can't. Someone It's like a car was sitting on my leg for 2 hours." Right. And so, these things, by eliminating all these little things that were involved with the classical aspects of surgery, I refined my technique to be less and less invasive. And I realized on the back end, the patients were incredibly happy and satisfied, but they could they they were like, "I got rid of my cane so quickly." Yeah. And I my patients sometimes it's it's a joke that sometimes that what they joke about. They say, "The physical therapist comes to their house typically the first couple weeks." And they open the door and they the patient walks up to the door with nothing. [laughter] And they're like It's Let's say it's a man. They say, "Okay, is your wife Where's your wife? Is she" He goes, "No, I'm the one that had the surgery." They're like, "But you're walking around." Yeah, I go, "Because they the results are just incredible." Wow. But I also think that like the neuro connectivity to your muscles Mhm. and activating your muscles. For example, like you go to the gym and you're like, "I want to work on my glutes and my quads." If you do really focused exercises on those muscles, you start activating those muscle fibers, you start getting neuro transmission to those muscles to activate those muscles. Mhm. So, by the prehab we talk about is getting you into that surgery, whether it's a shoulder surgery or knee surgery or hip surgery, activating the muscles around that joint, also trying to mobilize the joint, try to stretch Prior to surgery. Prior. Yeah. Sometimes you can't because it's arthritic and it's damaged, but as much as you can to to stretch and mobilize the fibers and then increase blood flow and connectivity to your muscles. And so, then when you come in, your muscles are activated and you have a much better easier time to activate those muscles again. I don't think that a lot of people think about getting in shape for surgery, right? And and we talked about this a little bit, too. I had some experience with the NFL Alumni Association where

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with the NFL Alumni Association where they were you know these athletes after they had retired from the league were having you know surgical interventions. I mean the ones that had trauma went right away, but but the repetitive use injuries that you know built up over time and now they need rotator cuff surgery or or knee hip or shoulder surgery. And the difference in outcomes just by rehabbing them, I guess, you know, and getting their hemoglobin A1C under control, getting their some of their inflammatory markers like C-reactive protein under control, getting them on on a good clean diet to lower their inflammatory cascade. Absolutely. So what would be in a perfect world, I'm coming in for a knee procedure, let's say a joint replacement. Yes. And what does a prehab cycle look like for you? How far out and what does that map look like? we like to get to people as early as possible obviously for for many different reasons and I think that way I look at it is like we try to be at the best we can be. We try to create the best surgery, minimally invasive, I use robotic technology. We're doing so much to make that operation great, but if the base, the foundation is poor, Mhm. no matter how good you are, you can't get a great result sometimes. And so we love to get to people many months before. Let's say 3 months, even maybe 6 months if possible to get them organized especially with their inflammation in their body to lower the inflammation, to work on their diet, and then also whatever supplements they need, whether it's like I'm a huge fan of your amino acids. Like I go all over the world and talk about The perfect aminos, which is a which I think is a incredible supplement. It's so easy. And we're right now with the patients, we're getting them on perfect if they let's say they're not taking it and let's say they want surgery quickly, we will put them on perfect amino every day all the way up to the surgery and then

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all the way up to the surgery and then at least for 6 weeks after. Most of the patients love it so much they stay on it for the rest of the time. They just I take it every single day. I take that, H2 tabs and a mineral salt every single day. do the same myself. Absolutely. And I take the mineral salt. [laughter] Yeah, I take it all. I'm a believer. If you look if your panchy looks exactly like my panchy. [laughter] So so I do it. I believe I'm a firm believer. And I just think that putting people on those programs, you're you're creating an environment for them to to gain prevent as much muscle loss as possible so they can gain the muscle [clears throat] back much quicker. You're getting rid of the the antioxidants in their body to just rid themselves of all this stuff. But also remember, we're giving them a lot of poison. We're giving them anesthesia. We're giving them narcotics. We're giving all these horrible medications that Right. that they patients don't like taking them but they have to in the beginning cuz it hurts. But to to rid themselves of all this stuff is this these supplements are very key to do that. I love that you're talking about, you know, diet lifestyle factors even prior to surgery. And I know that you and I have very similar viewpoints on sedentary lifestyle. And you know, when I was really drilling into your background, you you spoken openly a lot about how very often the problem is not um in the joint. It's it's from the lack of mobility causing the joint to now be dysfunctional. And I think that conventionally you would think the opposite, right? The more I use it, the more I wear it out. Um, but your discussions around synovial fluid and things like that and that mobility is critical for the for life extension of our joints. Absolutely. And and I think it's not only weight training, resistance training, it's also stretching, working on your flexibility. Like keeping the tendons and the

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Like keeping the tendons and the ligaments around the joint flexible, so there's natural movement. Because we know if I put your leg in a cast for 6 weeks and your knee doesn't move, your cartilage breaks down. Your your cartilage breaks down from from lack of movement. Lack of movement and load. Correct. Right? Okay. Yeah, and because because naturally when you move, the cartilage is on the the surface of your bones, they have water, the synovial fluid goes in and out of those cartilage cells by movement. So, the more movement you have in a joint, the more natural environment of the cartilage will exist and it will be better for your joints to move. But also, it's the muscles around it. And you know, like we see their spine patients who they get spinal cord injuries and they lose 30 40% of their quad, they get knee pain. They have a normal knee on an MRI, but their knee hurts cuz they don't have the strength. Right. So, it's build it's making sure that they build up that power and that strength in their legs. But the I tell every patient, you need to walk every day. You need to get out and walk and move because it's so important especially as we age Mhm. for balance, for mobility, for your whole system. And I talk all about this all the time with patients is the kinetic chain. Yeah. So, the minute your foot touches the ground, there's forces going through your leg, through your back, through your whole body. And so, by walking, you're activating that whole kinetic chain in your body as opposed to just doing like a bicep workout or just doing like a quad workout. You're working on all the little muscles all throughout your body. Yeah. And I mean, I think you know, walking is so uniquely designed to do everything that we need to live a long healthy life. I mean, it's it's it it circulates lymphatic fluid, you know, it's it's actually a part of our detoxification pathway. You know, that's why sedentary lifestyle is the leading cause of all cause mortality. When I was in the mortality space, it was fascinating that sitting had become the new smoking. Oh, yeah. You know, and and as an orthopedic surgeon, you're saying it's just as detrimental to the joints.

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detrimental to the joints. Absolutely. Yeah, it makes your joints break down. It it makes you it creates a lot more trouble and degradation of your cartilage and all your joints. But specifically the weight-bearing joints. So somebody that's in a position where they're considering a joint replacement, probably out of necessity. I mean, most people don't get them done cuz they don't absolutely have to all the time. [laughter] What's I want to talk about what's unique about this minimally invasive muscle sparing robotic surgery because there not a lot of orthopedic surgeons that are highly skilled in that area. And and you are the not just the thought leader, but you're you're also you train other physicians on these procedures. You're also affiliated with a number of professional sports teams, heavily weighted towards basketball for some reason. Yeah. I just I've been I work a lot in NBA and NHL, too. Yeah. Listen, there's what I share on this podcast and then there's what I share with my inner circle. If you've been following me for a while, you know how I hold nothing back here. But my VIP community, that's where the real magic happens. Picture this, you're struggling with energy crashes, brain fog, or just feeling like you're not operating at your peak and you don't know where to get real answers. But here's what really sets this apart. You're not just getting my insights. When I have incredible guests on the podcast, VIP members get to submit questions for a private podcast segment. So that world-renowned expert we just interviewed, you get exclusive access to their knowledge tailored to your specific situation. This section is under the private podcast section in the Ultimate Human Community. And speaking of exclusive, you're getting my personal protocols, the exact tools I use for water fasting, gut optimization, and morning routines that have taken me decades to perfect. This isn't theory, this is what works in the real world. The community launches challenges throughout the year where you get direct access to me and my network of experts. It's like having a personal health advisory board for less than $ 100 a month. Your health is your wealth and this investment pays dividends for life. Join the VIP community at the

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Join the VIP community at the ultimatehuman. com / vip and step into your ultimate potential. Now, let's get back to the Ultimate Human podcast. I I think trauma is the one thing, right? We understand trauma in sports and, you know, anytime you apply severe trauma to the joint, you're going to actually need need to have surgery. But, repetitive use injuries is is something I think is, you know, a broad category where people have just worn the joints out or they've had poor biomechanics to the point now where they're considering a replacement. Yeah. What makes what you do with minimally invasive robotic surgery? First of all, I don't think a lot of people really understand what robotic surgery is. Like, you don't leave the room and a robot does it, right? Okay, go ahead. [laughter] I'm not I'm Cuz I feel like Tesla's going to try to do that soon with their a sauna or cold plunge while the surgery's happening, you know. They can already wash your dishes, dude. [laughter] I mean, they can drive your car. So, you Exactly, No, I think that So, what what we used to do before robotics became the mainstream or or not not sorry, not mainstream, but before we had the opportunity to use robotics, we were doing the same operation essentially for everybody. We were kind of aligning joints. They said, "This is the best way for this joint to be stable and this and for it to be aligned properly." Mhm. What we do with robotics is we get a CT scan of the joint. Let's say if we talk about the knee. We get a CT scan of your knee. Now we know literally your alignment from your hip down to your ankle Mhm. rotationally in all three planes of of the body. We know exactly where your knee lies. Right. And then from that we understand the size of the bone the the appro the approximate sizing of the implant. Mhm. And then during the surgery I stress your ligaments. Not somebody else's. Not not based on some like research number. It's basically how your ligaments respond. And then based

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your ligaments respond. And then based on those responses of the ligaments we get a set of numbers and I adjust on a computer screen the implant to accept your ligaments. Ah. So it aligns your body to exactly the way your body's aligned. So you get the proper center of rotation. So that allows your leg to be in the perfect alignment. Not somebody else's Gary Brecker's alignment. The way your knee is aligned and your knee is is balanced. But also the sizing is perfect and the alignment is perfect. So we're literally putting it in because if you look at the data on total knees let's say 80% say I like it 20% say it feels weird. It doesn't feel like it's right cuz we're putting it in this weird way. Yeah, you can't put like a perfect hinge into somebody has genu valgus or genu varus or you know wide wide hips and narrow uh you know angle versus narrow hips and more of a straight angle. So so you're accounting for that anatomical physiology on a per person per patient basis. Absolutely. But it also imagine someone has a weird shape to their femur a weird shape to their ankle. They had a broken ankle years ago. You're getting you're you're going to account for all of that. Yeah. And then what also makes it incredible is is idea called haptic technology. So, when you're cutting the bone, the robot knows exactly where the bone is in space. So, the saw will never leave the bone. Really? Absolutely. So, I'm a big guy. I'm 6'4". held the thing in your hand like Yeah, no. It's It's on the robotic arm. So, I tell people like I'm 6'4", I weigh about 215 lb. If I lean all my body against that robotic arm, it will not move. Really? When when we used to do knee replacements and people still do them without the robot, the saw would exit the bone and that would cut all your tissue and create more scar tissue, more trauma, more damage. So, the haptic technology keeps the saw or the cutting device within the parameters of the bone and it will never exit.

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and it will never exit. Wow. makes it so so perfect. And that's that's really where robotics is a game-changer. And now we have it for the hip, we have it for the knee, and we have it for the shoulder now. Mhm. And so, the accuracy of putting those implants in and getting the actual center of rotation where your muscles work the most efficiently, where you have the best result with range of motion and stability, you get all that without having to like use like you know, kind of primitive x-ray or something that you don't understand. Now you know three-dimensionally exactly the way it's going to be. So, when you have a a selection of I'm just curious. I mean, when you have a selection of like different um prosthetics, you know, knees for example. Um I always thought everybody got the same knee. No. Right. So, you know, like Stryker just made 200, 000 knees and you just bought it and stuck it in there. Well, I know. It's Well, I use Stryker. That's who the robot robotic company that I use. trying to shout them out. Whatever. but I but but yes, so they come in different sizes and different kind of alignments and stuff like that. And that's what you pick. So, like for example, like a woman may be a size two or like I may be a size five, but we have different sizes, but it's the positioning of that implant to get the best range of motion and the best best movement, but also we're not damaging any tissue while we're doing it. That's the big thing, right? Huge. are so So my mom, Judy Burkos, is in the audience with us today. Hi, Mom. Um she had bilateral knee replacement. I wish we had known him when you had your knee replacement. [laughter] Cuz she actually had to have one redone. Uh she had a an infection in one. Uh so they put a temporary in. Oh yeah, that's the two-stager. Yeah, that I think had like antibiotics in it to kind of clean clean up the infection. I know. It wasn't That's tough. That's a tough [laughter] recovery, yeah, and um truthfully what happened was um and I've I've talked about this a number of times and I can say it while

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number of times and I can say it while my mom is here is, you know, she went to this rehab facility post-surgical rehab facility and uh they didn't get her out of bed Mhm. for almost 45 days, except for like restroom and things like the Oh my god. And this was an an issue because there was this little loophole where um one of the rehabilitation specialists could come in and if my mom denied therapy uh they would get paid for the therapy and they would just leave. Oh. So Yeah, I found out that this you know, young therapist was coming in on on the days she was supposed to see my mom and if if she said, "Okay, you know, you ready to go, Mrs. Burkos?" And she goes, "Oh, I think I need to, you know, go to the bathroom." She go, "Oh, patient denied therapy." And by noting the denial of therapy, they didn't have to do the rehab. So it set her back tremendously. And then she had the knee replacement and she was starting so far beyond behind the eight ball. The muscle loss just from that loss [clears throat] was incredible. And she's working her way out of it now, you know, I have a rehabilitative specialist comes to the house what, three, four days a week. Um Dr. Evan, big shout out to you. And does the post-surgical rehab and gait analysis and things like that. And it's helping a lot. So my father with his gait. But I wish we had known about the prehab. Yes. Um so, for for someone like my mother, what would you know, where where we've decided yet it needs to be a bilateral knees and you do them both at the same time, right? Sometimes, yeah. In the right patient, yeah. Um and with this robotic surgery. What would that prehab timeline look like and and what kind of biomarkers, if any, are you looking at before? I mean, we we like I mean, we obviously work with professionals that that do the the labs and we we like to look at, you know, A1C. We like, you know, we like to look at all the inflammatory markers. C-reactive protein. all these inflammatory markers, sedimentation rate, different things to

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sedimentation rate, different things to make see look what people's inflammation is and also to look at all other aspects of their their health, you know, whatever they need, as many biomarkers as they can check, you know, to just make sure that like even heavy metals and all those kind of things to just get them detoxed from all these things. Because I just think the more optimized you are. But like I said, I like to get to people as early as possible. Most of the time we have about three months you know, to get them going. And so, getting them prehab and getting them through that process where they're they're getting stronger. But we also empower the patients. We say, "You're getting up day one and you're getting up immediately and that's your job." And we Walking the day of surgery. We We our goal is to walk within an hour of the surgery. Oh. I mean, so you so The nurse is always saying All right. have Snippy do your surgery, you're up and walking day one. Yeah. [laughter] So, so there's there's an enormous amount of data showing that if you get up and walk on your joint replacement immediately, your confidence goes through the roof of a of trusting the joint. Wow. And I tell this to patients all the time. I'm like, "Your joint replacement is not like a delicate egg. It's not going to break. It's so strong. This is metal and plastic. It's really strong." So, we get them immediately up. And then, when they have that confidence, they realize, "Oh, wait. I'm okay. Yeah. I can put my weight on my leg. It's I'm not going to collapse. I'm not going to fall and break something. I can actually put pressure on it immediately." Yeah. And that's one of the reasons it's a good segues is one of the reasons for us for me we want to I'm a big passion of of my big passion is controlling the episode of care for these patients. Is how do we get the right people to touch our patients and have access to our patients through that process? Because in the medical system now, it's hard. Yeah. Because in a hospital, some therapists buy into the system, they don't. Some internists buy into the system, some don't. And so, I have spent my whole life my whole career trying to

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my whole life my whole career trying to control that episode of care to get the the best physical therapist, the best person to check all those markers, the best person to give them the right medication and the right treatment to get them through that process. And we're starting to evolve into that. Where where it's it's all about like all the things that you do that I love. I was very flattered that you invited me in to to be a part of your rehabilitation facility and bring some of my biohacking tools there and We would love to advice on how we could do, you know, better recovery [clears throat] through different biohacking modalities. And that's what we want. We want a whole system. Because I think like it's almost like Yeah, you have to have a surgery, and it's a process, but you can save that person's life. Mhm. You know, if you you do this whole analysis on them, and you realize, "Hey, you need to lose some weight. You need to get your inflammation markers better." You can make their entire life better. Yeah. You know, their their level of activity, their level of resilience and strength, you can change their life completely. Yeah, I love that. I also I like that uh you're outside the box um and and you have a very progressive attitude towards things like PRP, um exosomes, stem cells, and fascinatingly and very exciting uh you know, peptides. Yes. Um you said that uh you you're only on peptides yourself, but [laughter] um love them. I love them. a good sign. Um but, you know, talking about peptides specifically for a moment, what what peptides have you found in your surgical practice and your uh rehabilitation of patients post surgery have been the most effective? Like, what are your go-to? So, my go-tos are BPC 157, TB 500, and ipamorelin, which is a stimulation of your own growth hormone. Those are the main ones that we use and and those are the ones that we tend to see great results with. And the peptides have been a game changer because we're putting people on these peptides and a lot of them are getting better without

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them are getting better without anything. Mhm. Like, I had a guy in the office the other day who had rotator cuff tendonitis. We put him on BPC 157, TB 500. He he texted me a month later, he goes, "I'm 80% better." Really? So, it's incredible. And then I have my own story about peptides. So, I had all these patients on peptides. I had this horrendous Achilles tendonitis. It was so bad, my patients are like, "Hey doc, why are you limping around?" Yeah, it's not a good look to be limping as an orthopedic surgeon. It's not a good look. It's like being a skinny chef. It's not a good [laughter] look. Exactly. So, I had this and so I had a few patients, actually a couple patients from Vegas, and they were all on peptides. And I'm like, "You know what? I just got to put myself I put myself on it." Six weeks, cured. I I had it for 2 years. It was gone. Like, not even if someone hit my Achilles, I'd like go through through roof. It was so painful. And so, it literally just healed it. And so I'm a huge believer in it. I also think for me, I'm a surgeon, but my single the principle that I've lived my life by is how do we avoid surgery? When people come to me and a lot of people come to me in LA and from all over the country because they say, "Go to Snibbe because if you don't need the surgery, he will tell you." Really? Because I always say I'm more popular from the people I didn't operate on than the ones I did. Because I like to look at things and look at there and I ask the questions. I always tell patients, "I don't operate on your MRI. I operate how you feel." I love that. Yeah, I saw that in your record. You don't You could have a meniscus tear, a little arthritis and you say, "Well, I can play golf 5 days a week and I'm exercising, working out." So I'm like, "Well, what what's the problem? Just go keep doing it." And then the other thing is all these injections. These injections help continue the process of healing and promote healing into the joints, increase blood flow, lower inflammation, and all of these these injections that we do, whether it's PRP, whether it's exosomes, are going to keep evolving. I

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exosomes, are going to keep evolving. I mean, you're you're on top of this data so much. No question. We're we're just at the tip of the iceberg of this thing where we're going to be able to modulate these things based on what you have. So they say, "Okay, you have arthritis, this is what we use. You have meniscus, this is what we use. Rotator cuff tendinitis, this is what we use." And I think that that's the key for me is that I'm always asking the question, "How does this affect your life? How is it what's the impact?" I'm like, and then I always tell them, "You can always have surgery. Right. You can have surgery tomorrow, you can have surgery 3 years from now, you could I can always operate on you and if I do it, I'll do a good job. Right. But right now, you don't need it. Right. Go get your biomarkers better, go get your nutrition better, lose a little bit of weight, get your diet organized, Mhm. and let's see what happens. You know I'm all about optimizing performance and lately I've been using the Ion weighted vest during my workouts and it's been a game-changer. It isn't your average weighted vest. It's designed to fit like a second skin activating your core improving blood flow and even helping you with recovery while you train. What I love most is that the weight is perfectly distributed. It doesn't pull on your shoulders or throw off your alignment. Whether I'm doing strength training or cardio or just taking a walk, I'm burning more calories, building muscle and pushing my endurance even further. If you're serious about leveling up your training and unlocking your full potential, check out the Ion weighted vest at iongear. com. That's aiongear. com and you can use code ultimate for 10% off and start training smarter today. Now let's get back to the Ultimate Human podcast. You know you and I have a friend in common Ram Dandillaya. Yes. Is it Ram or Rum? Okay, Rum Dandillaya. You know every every other Indian doctor I know is named Patel. So he's like Exactly. [laughter] I think you almost have to be a Patel if you're Indian and you're a doctor. It's like I think so. Yeah, there's a lot of it's like Smith's in India.

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like Smith's in India. So but but he and I connected over Dana White's journey. He was his uh cardiac doctor. And he's out at at Cedars where where you are. Yes. What I really find fascinating is what you guys are doing with this uh more than $ 100 million center that you're building for not just surgery but pre and post surgical rehab bringing biohacking modalities like red light and hyperbaric uh uh you know chambers and and things like that to the table to really help patients accelerate their healing process but at the same time just improve their their cellular biology. How how is it that you're, you know, such a classically trained allopathic physician and surgeon, um, but you're willing to consider and you're open to um some of these biohacking modalities and therapies that I would call non-mainstream like red light and and hyperbarics and I think that when like we said earlier, I think that, you know, it's like you're an artist, right? And you have a [clears throat] canvas. You want that canvas to be good quality canvas and that you can paint on. You make that beautiful picture. So, if the canvas or the patient is not quality, they're not they don't have good tissue or good metabolism and good health, no matter how great of a painting you draw, no matter how great of a surgery you do, you're going to have a bad outcome. Yeah. You're going to increase your infection rate, you're going to have wound healing problems, you're going to have muscle wasting and muscle loss, and sometimes they can never gain it back. Yeah. And so, like I said earlier, how do we control the episode of care? Mhm. Because it's not a trans transactional thing where like, "Okay, you come in here, you have a knee replacement. Goodbye. I'll see you later." Right. It's now a process Mhm. where we can take them through and try to control some of these things and also mitigate risk Yeah. and try to make sure that they don't have they have a lower chance of

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don't have they have a lower chance of the given the best chance for the wound to heal. Put them in a hyperbaric oxygen chamber. Yeah. Put them in red light to increase blood flow so their wound healing is better. So, they get better blood flow to their muscles and their the microvasculature. Yeah, we talked all about that. stuff is just such a huge part of it. And I think that for me, I've always thought that's why I embraced robotic technology because I said, "This is where we're going. This is where the technology needs to be." And I don't want to be in the backseat. I want to be driving this. But then by building this beautiful hospital that will be done at the end of this year, you'll come see it. Yeah. We'll have literally a hospital. Building a hospital, 70, 000 square foot hospital. ground up? from ground up. Just a beautiful, gorgeous hospital that we can control all these aspects. So, we can put hyperbaric red light inside of it. Because when you work in a hospital system, there's so much regulatory issues that restrict you from doing the things that you want really want to do. And so, I said to myself, I said, "How do I How can I make the experience on all levels amazing?" But, it's also the like we said earlier, the non-surgical patient. You know, you have a meniscus tear, and you're going to get an exosome in your knee. I love that. I want you doing all this stuff, too. You know, I want you doing the red light and the hyperbaric and the the peptides and the aminos. I want you on all this stuff to optimize your recovery, even surgical or non-surgical. Yeah, I love that. I mean, and I think the the future of medicine in general is this whole patient approach. I think, you know, for for so many decades, we've we've only treated the one little narrow symptom that's presented. Like, you know, the joint has degraded, let's replace the joint. Right. And and we just focus on that event, not this pre-habilitation and post-habilitation. You know, I I had an orthopedic surgeon named Dr. Alex Di Simone, and I'm grateful to that

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Alex Di Simone, and I'm grateful to that man to this day because in 2009, I had an ACL and MCL, and I actually cracked the lateral half of my tibial plateau in a bad knee injury. I wish I had a great story. The story's terrible. [laughter] I'm going to make something up, so it sounds like heroic. But, the truth is I'd had a few cocktails and and decided that the one jiu-jitsu class that I took at the YMCA qualified me to wrestle a a wrestler that was my business development director. Oh my god. was like this short little spark plug and and we got to chatting at at a at the bar at an insurance conference and I was like, "Hey, let's just go up to the room and figure it out." Oh, yeah. I'll hip toss you all over this place and I [laughter] was like You know, it's like one of those like Hilarious. You know, like the guy that's taken two boxing classes and I'm like, "No, don't grab me like this. Grab Grab me like this. Don't don't stand there. Stand over here. Put this leg here and then I'm going to like throw you across the room. [laughter] He's like, "We're going to wrestle." And he handedly with my ass and in the process, you know, broke my leg. Dislocated my knee and and um But but I remember what he said to me after surgery was and and he said, "I need you to hear these words because it's the most important thing you're going to hear for the rest of your life and this will determine the use, your pain level, your functionality for the rest of your life." He said, "Surgery is 30% of your journey and your surgery went exceptionally well. I did a great job. You got great tissue in there. Joint's very healthy." He said, "70% is going to be how dedicated you are to your post-operative rehab. And at some point, you're going to feel like you're tearing pages out of a phone book meaning like your progress is going to be so minimal. You know, for the first few weeks it's like big progress. Yeah. um Absolutely. And and I never forgot that and I just I

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And and I never forgot that and I just I hardcore dedicated six months of my life to just rehabbing that joint. And you know, a few years later I was age group champion for the state of Florida in medium distance triathlons. I was you know, I and to this day, God bless him, I have zero pain, no loss of range of motion. That's great. Um you know, knock on wood. Yeah. But he was you know, I I think a lot of patients think, "Okay, surgery's over. I'm going back to normal life." And they don't think about how much care do I need to give to this so that it doesn't I'm just not not buying myself a problem in 10 years. Absolutely, yeah. And I tell patients all the time, like I I take care of professional athletes. And Yeah, you mean your roster. Not don't interrupt you though. Yeah, like Clippers, the Lakers, the Sparks, the Kings, and the Angels, and assistant team physician ties to the Dodgers, uh Galaxy, and others. I mean, you're a monolithic mega giant. He's being very humble, guys. [laughter] Uh you know, with his career in professional sports. say, like I when you take care of professional athlete, they're back playing sometimes at 6 months. But then you have a conversation with them, and you say, "When did you feel?" If you ask the question, "When do you feel like you were back? Like when did you feel like you were explosive as you were before you got injured?" And a lot of them say a year. Yeah. Many of them say a year because it takes that long for those fast-twitch fibers in your muscles and the explosiveness of your body to be able to do that. It's also really important for us as orthopedic surgeons to look at the whole body. Like someone comes in with knee pain, you got to do a good back exam, you got to do good hip exam. You really have to check other parts of the body. For example, I had a patient the other day who I did a knee replacement on. He goes, "My knee replacement's hurting. I'm having trouble." And I examined him, and his medial collateral ligament was on fire. Like I just touched it, he went through the roof. And I examined him, and examined his hip. His hip was arthritic. He'd worn out his hip. Ah. And I'm like, "Because your hip's arthritic, you're cranking on your knee too much. So guess what? We replaced his

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too much. So guess what? We replaced his hip, and now he's great." Really? problem. So it's by looking, not being so, you know, hyper-focused on that one joint, is really looking at the whole person. You know, like, "What other surgeries have you had recently? Have you had a abdominal surgery? Have you had a back surgery? You know, how is your life right now? Are you under under of stress? What's your work-life balance like? You know, thinking about the whole person Mhm. is very important to understand what makes them tick, but also how to organize and customize their recovery or planning for their surgery. Yeah. So, you're building a hospital. Um you also launched your own shoe brand. I did. Which I think is so awesome. It's so fascinating. actually. It's really it's fun project. Yeah, I mean specifically designed around sounds like you did it out of need because you know, designed around people that are on their feet for longer long periods of time, which anyone that's in a hospital um and those are concrete or hard tile floors. Absolutely. Um you know, and standing on all that. I mean, I just notice it walking around my own place cuz we've got tile in here. If I walk around barefoot for too many hours just being in here I I It's a lot of stress on your body. of stress. Yeah, so I I spent about 4 years. My my partner is a chef and I'm a surgeon. [laughter] And so, the two of us looked at each other Chef and a surgeon got together made a shoe. And so, we we said our shoes are so bad. You know, we have these clogs that you can barely walk in or people just wear like a pair of Nikes or or Asics to the hospital and the the fluid gets through it and the padding in it wears out after like let's say 2 3 months. Mhm. And so, we said we spent 4 years designing a shoe, working with materials and testing them and going in the I would go in the OR with them and spend days working with them. He would work with them on in the as a chef. Yeah. And we slow and we put them on our friends and family and said, "Okay, how does this feel to you?" And finally, we developed a company called Snibbs. It's a parody on my name.

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a it's a parody on my name. S N I B B [clears throat] S and we created this amazing shoe and then we also now have multiple levels of shoes. We have shoes that are waterproof and slip-proof. Most of them are slip-proof. We have a a work boot. We have a clog. We have all different kinds of shoes for different environments and it's really not just a doctor chef thing. It's for anybody. Anyone that works on their feet, anyone that's out working and walking. People people wear them to work out. People wear them for long walks. And people like we have people wear them on movie sets when they're working those 12-hour days. All kinds of environments, but it's to basically take the stress of your body away. And we always say I would say about the shoes is like I want you not to think about your feet at the end of your day. I want you to come home and think about, "Okay, how am I going to enjoy my night? I'm going to have dinner with my wife. I'm going to go do something relaxing." I don't want you to say, "Oh my gosh, my feet are killing me." And so and and we realized by making great shoe wear, you take stress off your knees, off your hips, off your back. And that makes you perform better as a person, makes you feel better as a person, and it also we're also realizing that we're minimizing injury. And so we've done it we've done a couple projects. Actually, one one of them was at Caesar's Palace in Vegas. We gave 2 300 people shoes and none of them had a slip and fall over the course of about a 6-month period. And so we're realizing that we can actually have the potential to minimize injury for this because of the floor grip, the anti-slip? Exactly, the anti-slip and also the fact that the the shoe really captures your foot. And and [clears throat] we also designed the shoe to allow for swelling. Cuz your foot swells over the course of the day, it accepts that. And so those we're realizing that we can actually even benefit the patients and and sorry, excuse me, the patients and also the employees by not having injury. Which can take them out of their life and

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can take them out of their life and cause horrible problems for themselves. And what's unique about the padding? Is there something The padding is a special kind of padding. It's a special rubber material that we proprietary designed that basically has resilience and cushioning but it doesn't wear out in 3 months. It's not the same stuff that like if you have a running shoe like a Hoka running shoe. The Hoka running shoe is very cushy and bouncy bouncy and it's great for about 3 months. Right. 50 miles I think is what my son says he replaces them after. Exactly. So after that it goes but our shoe we're not obviously running in them but they have much more resilience so they last a year year and a half of of that cushioning. It's much more resilient. If you know me, you know I'm a huge believer in the benefits of hydrogen water. H2 tab delivers cost-effective portable tablets that generate ultra-clean molecular hydrogen at 12 parts per million. One of the highest concentrations on the market. With over 1, 300 published studies showing benefits of oxidative stress, energy, recovery, brain function and so much more taking charge of your health has never been easier or more cost-effective. Just drop a tablet in water, let it dissolve and drink it back. It's less than a dollar a day, science-backed and part of my daily routine. I never travel without this and it is my favorite bio hack. Visit drinkh2tab. com. That's drinkh2tab. com and upgrade your hydration today. Now let's get back to the Ultimate Human Podcast. Okay. Yeah. So for for you, you know, as an orthopedic surgeon being in this minimally invasive category of robotic surgery which I'm an enormous fan of. Um where do you see the future of orthopedic surgery going? Like what's like really exciting for you on the hi on the horizon? Is it faster healing through things like stem cells and

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through things like stem cells and peptides and exosomes and and different biohacking modalities or or is there new technology on the horizon that you've got your eye on that that you think is going to revolutionize orthopedic surgery? Or do you consider what you're doing right now to be the absolute most cutting-edge thing available? I think that I think I don't think that I think we're always changing and moving and learning and things are just being and they're going faster than they ever have been. I think the future of orthopedic surgery will be even less mini - less invasive than what we do now. I think that we have the ability with the robot at some point to have what they call automation where you basically you know, you open up you make small even smaller incisions that we make now where the the robot can go in and prepare the joint or prepare things for us with cutting even less tissue and even less materials. You have to still make an incision to get the implant in there but even less trauma to the soft tissues than we do right now. And so I think that's that's really important. I think that we already are using AI in when we get the CT scan AI kind of prepares a 3D model of the joint for us. So we use AI already but there's going to be even more AI on data. So what there's going to be happen is that in the future is going to be like, okay, I think this this person should have a hip that looks like this. And they're going to say, well of the last 5, 000 hips that were done in the United States that have hip just like this, this is the decisions that they made. They use this implant, they use this sizing, this positioning and those patients had 98% satisfaction. So we'll be able to use outcome data to correlate live during surgery to make sure that like we want to make sure that this person has the best result. Wow. So that that's a big part of it. There's also some and you may know more probably about this than me I do but there's there's also some data about muscle

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there's also some data about muscle mass. He special MRIs now looking at muscle mass. And yeah, and then all and all these and looking at the quality of your muscle. So, part of that prehab is that how do we quantify muscle mass? Like how do we know? We don't know. Like someone comes to me and they have a bad hip, they've lost a lot of muscle mass in their glute. Did they lose 50%? Did they lose 20%? We don't know. So, understanding the value a quantitative value of like how much muscle mass you've lost and this is how much you need to gain and we can check them post surgically to say you've gained back 80-90% of your muscle mass now. Wow. And so that those are some things, but I also think the biggest part of this in my life will be all of these these biological things that we can do to patients without having surgery. And how do we treat joints? Like for example, when you tore your ACL, right? Like is it important should you have gotten like 10 injections of exosomes over the course of a year into your knee to protect you from post-traumatic arthritis? Like what are the things that we can do to prevent these things from happening? And also we're seeing people get arthritis and damage in their joints just from wear and tear, but also from [clears throat] metabolically, right? They're like women they're postmenopausal, they lose their estrogen, they all of a sudden they wear out their joints. Wow. From from lack of estrogen. And so how do we understand that better? How do we understand why you have so much inflammation in your body cuz your diet is horrible Mhm. that you your knee wears out. And so it's just it's understanding these things on a higher level I think it's going to be the most incredible thing where people will all the things that you do that are so incredible that everyone will have access to that. I love that. I mean, what's an example of somebody that had let's say arthritic knees and you use some other intervention besides surgery? What ways [clears throat] have you intervened in? So, one of the simple things is meniscus tear. So, classically if you

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is meniscus tear. So, classically if you tore you tear your meniscus in your knee, an orthopedic surgeon like me would say, "Oh, we're going to go in there and nibble away that meniscus." Well, guess what? 30% of those patients, which is a big number, end up within 3 to 6 months with a knee replacement. Really? Because by just mess mucking around in the knee it up. going in and cleaning out just that little cleanout, it it's trauma. You know, surgery's trauma, so you're creating trauma inside the joint, which makes the knee deteriorate. Mhm. So, those patients, the simple injection would be platelet-rich plasma. You draw some platelet-rich plasma, you spin it down, you inject it into the knee. Sometimes if they have a little bit of arthritis, I'll put hyaluronic acid with it. Mhm. But that simple injection, many patients get 70 to 80% better from one injection. Really? Absolutely. PRP or uh hyaluronic acid or exosomes, yeah. of that. Or sometimes we'll do exosomes. But the thing is, we get patients better with that simple meniscus injury. And I tell patients all the time, I said, "I'm 53 years old. If I tore my meniscus, I wouldn't let anybody touch it." Mhm. Because I see so many problems with this meniscus surgery. Yeah. And so I I treat them with with exosomes, with PRP, a good physical therapy, supplements, and then they get through it and they're they're back with they're back on the tennis court, they're back playing golf, they're back exercising, and they're fine. Sometimes it takes a couple injections to get them across the finish line. I mean a couple of injections versus a full, you know, joint replacement is or or surgery and then a joint replacement. Absolutely. It's is a much easier road. Much easier. And that's something that is is in my it's unfortunately it's not the mainstay in all practices, but in my practice, that's what we do every time. And that's why a lot of people come to me. People think like, "Oh, they come to Dr. Sim because he's going to operate on you." They got to come to me all the time because they say, "I heard you do this PRP in the hip and to get me better." And and they're like, "That's why I'm here." Like I saw three surgeons. They all want to operate on me. Right. And and we do PRP and they're like, "I got better and I I can't believe I was going to have a surgery and you just

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going to have a surgery and you just fixed me with a simple little shot." Yeah. And even in arthritic patients, these exosomes uh the platelet-rich plasma, hyaluronic acid, you see improvements in those arthritic knees. They may not have Yeah, dramatic anatomical issues, but pain. Absolutely. And then obviously, every patient is different. I mean, we analyze the MRIs carefully. We look at the deformity of the knee, how much disease they have, how much they don't have. And you know, it's I always say, "When you come to me, it's like a picture. I'm taking a picture of your knee in this one moment in 2026." And things can change and move and sometimes it doesn't change, but we try to optimize that joint and get that joint happy as it can be right now. You know, I I've It seems like I have a lot of friends for some reason right now um that are having total shoulders. Yes. Um and not a single one of them has not told me that it was the most brutal thing they've ever been through. And like even though they prepared for it before s - surgery, like coming out of it, the length of time getting back to full mobility um for them. TJ Dillashaw is one of my buddies of uh UFC fighters getting ready to have one. Um but I have a number of friends that have had them for some reason and uh I wonder if there's in you know, in in your case, do you do shoulders? I do. Okay. And are there minimally invasive uh you know, robotic procedures that that lessen that kind of recovery time? Absolutely. So, in a shoulder, a shoulder's a unique joint because it's like I call it like a golf ball on a golf tee. The socket is a tiny little bone. It's called the glenoid. It's tiny. It's like some of them are like a quarter, maybe a little bit bigger. It's like it's this tiny little bone. The ball is big. But to put an implant on that little bone, that little golf tee, the socket is is very difficult cuz you have to fire a pin down the bone that's in the perfect alignment. Mhm. And so the robot, which is incredible,

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And so the robot, which is incredible, I was on the development team for the robotic shoulder. Really? The ability to get that pin in the perfect position every single time with the robot is like as accurate as it can be. It's it's incredible. Really? So that makes a big difference because now you're putting the implant in the right spot, but also you're minimizing bone loss. So remember we talked about haptic technology? The the robot prevents you from taking too much bone or causing too much trauma around the joint. Mhm. the robotic technology will make a big difference. It is making a big difference in the way people recover from those surgeries and the way they respond from those surgeries because sometimes the preparation of the bone and all the tissue causes a lot of trauma around the joint. getting in there. You got to do a lot of damage getting in there. but the also the issue with the shoulder, too, is like we talked about muscle mass. A lot of these people had these very arthritic shoulders that don't move, and so they have a lot of muscle wasting. So it takes them a very long time, sometimes a year, to gain all that muscle back. Right. But again, by doing things like Perfect Amino, by taking certain things in your body to help maintain your muscle mass and build your muscle mass because sometimes just you on your own eating, you know, fish and vegetables is not enough. Right. [laughter] Yeah, So it just pick your shoulder. Exactly. So you need supplements that will help build those things. Yeah. Dr. Snead, this has been amazing. I know my audience is going to be uh so excited to to listen to this podcast and hear through this information. I love thought leaders like yourself that are really patient-centric and thinking about what is the best possible outcome for this patient to get back to full life and and forget that this surgery ever ever even happened and the focus on pre-habilitation, post post-habilitation, minimally invasive surgery and the use of things like peptides and

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peptides and uh stem cells and exosomes and platelet-rich plasma and all of the biohacking modalities, you know, tells me that you're you're really focused on on the whole patient journey and I really applaud you for that. I wish Thank you. uh you know, more of allopathic medicine would take this this whole patient approach. It's it's really exciting. Um but uh so for my audience that wants to find out more about you, where where can they find you? Are you on social media? on social media at Dr. Snibbe, uh Dr. Jason Snibbe on my Instagram, on Facebook. Um I have a website, Dr. Jason Snibbe. Okay. So they can find me all over. Okay, I'll put links to it to both of those in the show notes so people can find it and I'll put links to your new When is your new this new hospital opening? will be done being built in December. We'll probably probably Yeah, we're cranking. And and then we'll probably do our first cases like January, February. Okay, and is this all outpatient? No, inpatient. You can stay overnight. Yeah. Wow. So we'll have physical therapy in the place. They'll stay a few nights, you know, and then they'll go home, but we'll have all of that there and then we're we're going to and then we're building out this whole thing. So we want to do this whole longevity kind of thing. Well, I'm going to do it with you. Yeah, I love it. [laughter] I would love that. It'd be a dream. Yeah, so I'll come out and see you next month and we'll talk about how we build the the most impactful rehabilitation center for these post-surgical patients that that the world's ever seen. it. So I wind down um all of my podcasts by asking all my guests the same question. There's no right or wrong answer to this question. Uh but what does it mean to you to be an ultimate human? To be an ultimate human is to be a person that for me to be to help people. Mhm. To really, really help people in what they their their struggles in their life and obviously for me orthopedically. And to be an ultimate human, I want to do whatever I can on every level of their life to make them move and perform and go through life comfortable and happy and strong. Mhm. And to me that is the ultimate for me

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And to me that is the ultimate for me being the that is what I would say is the ultimate human for me. That's awesome, man. Well, I think you're an ultimate human, so [laughter] Thank you so much. For me that means a lot. Yeah. Dr. Seedman, thank you for coming on the Ultimate Human podcast. We're going to head over to my VIP room now. I've got some VIPs waiting for you to ask questions. They they knew you were coming on the show and they asked a list of questions, so we'll go in and and speak to those guys. And until next time, guys, that's just science.

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The Case for Better First Decisions

A painful knee or ligament injury is not automatically a straight line to surgery. Imaging, symptoms, tissue quality, and long-term joint health all matter. Good medicine slows down enough to choose the least traumatic effective option.

Peptides Need Clear Boundaries

BPC-157 and TB-500 are discussed widely, but human evidence remains limited and regulatory status varies. They should not be treated as casual recovery tools, and this article does not provide dosing, sourcing, or protocol advice.

Prehab Builds the Return

Strength, range of motion, and movement quality before an operation or intervention can shape the outcome afterward. Recovery begins before the repair.

"The useful stress is the one your body can answer."

Practical Takeaways

  1. Seek a qualified clinician before choosing a joint intervention.

  2. Be cautious with peptide claims, especially when evidence is early or anecdotal.

  3. Use prehab to build capacity before and after treatment.

Words Worth Hearing

The practice is not about chasing intensity. It is about creating a signal, then giving the body room to adapt.